How far do you have to get in a skill (Proficient Familiar Attempted Not started etc) To be able to Master it with a mastery challenge

This is my progress in a course that I am pretty proficient in but don't want to waste my time having to do the course test over because you miss one because of a stupid mistake and you have to complete it and start over. This is what happened to me, I would just skip all the questions to start over because I wanted 100% on it but it totally messed everything up and my ocd gamer brain wants everything completed but my logical side knows I need to move on to harder things. (so don't skip questions if you can help it!) So I am wondering, if everything is at least familiar and I do mastery challenges twice a day, will I eventually get 100% in the course or do I have to get certain skills higher?